Trial finds diaphragms and lubricant gel add no benefit for HIV prevention when using condoms

July 2007

July 13, 2007 – The Methods for Improving Reproductive Health in Africa (MIRA) trial found that the use of diaphragms and lubricant gel in addition to condoms for HIV prevention is no more effective than condoms alone. Ibis was a collaborating partner in the MIRA trial, led by researchers at UCSF, which enrolled more than 5,000 women in South Africa and Zimbabwe. The results are reported in an article published today online and in an upcoming edition of The Lancet. 

To date, male and female condoms remain the only proven barrier methods for HIV prevention. Ibis supports continued research into new HIV prevention methods that give women and girls the power to protect their health.

Additional resources:

  • For detailed information about the results, including a Q&A document, a fact sheet, and links to press coverage visit the Cervical Barrier Advancement Society, coordinated at Ibis.
  • Read the article and related commentary at (Free registration required to view the article. Commentary available to subscribers only.)
  • Learn more about female-controlled methods for HIV/STI prevention.
  • If you have any difficulty accessing these links or materials, please email admin(at)